Publications

Zakirov B, Charalambous G, Thuret R, Aspalter IM, Van-Vuuren K, Mead T, Harrington K, Regan ER, Herbert SP, Bentley K. Active perception during angiogenesis: Filopodia speed up Notch selection of tip cells in silico and in vivo. (2021) Philosophical Transactions of The Royal Society B; Mar 29;376(1821):20190753. doi: 10.1098/rstb.2019.0753.

Costa G, Bradbury J, Tarannum N, Herbert SP. RAB13 mRNA compartmentalisation spatially orients tissue morphogenesis. (2020); The EMBO Journal; 39(21). e106003. doi: 10.15252/embj.2020106003

Herbert SP, Costa G. Sending messages in moving cells: mRNA localization and the regulation of cell migration. (2019); Essays in Biochemistry; Jul 19. pii: EBC20190009, doi: 10.1042/EBC20190009

Page DJ, Thuret R, Venkatraman L, Takahashi T, Bentley K, Herbert SP. Positive Feedback Defines the Timing, Magnitude, and Robustness of Angiogenesis. (2019); Cell Reports; 27, 3139-3151 e3135, doi:10.1016/j.celrep.2019.05.052. PMCID: PMC6581738

Costa G, Lovegrove HE, Herbert SP. Endothelial cells divide unequally to sprout fairly. (2017); Cell Cycle; Apr 3;16(7):595-596. doi: 10.1080/15384101.2017.1294942. PMCID: PMC5397259

Costa G, Harrington KI, Lovegrove HE, Page DJ, Chakravartula S, Bentley K, Herbert SP. Asymmetric division coordinates collective cell migration in angiogenesis. (2016); Nature Cell Biology; 18(12):1292-1301. doi: 10.1038/ncb3443. PMCID: PMC5548250

Sacilotto N, Chouliaras K, Nikitenko L, Wei Lu Y, fritzsche M, Wallace M, Nornes S, García-Moreno F, Payne S, Bridges E, Liu K, Biggs D, Ratnayaka I, Herbert SP, Molnár Z, Harris A, Davies B, Bond G, Bou-Gharios G, Schwarz J, De Val S. MEF2 transcription factors are key regulators of sprouting angiogenesis. (2016) Genes and Development; 30(20) 2297-2309. doi: 10.1101/gad.290619.116. PMCID: PMC5110996

Herbert SP*, Cheung JYM, Stainier DY*. Determination of Endothelial Stalk versus Tip Cell Potential during Angiogenesis by H2.0-like Homeobox-1. (2012) Current Biology; 22(19), 1789-94. doi: 10.1016/j.cub.2012.07.037. PMCID: PMC3471071 (* co-corresponding authors)

Herbert SP, Stainier DY. Molecular control of endothelial cell behaviour during blood vessel morphogenesis. (2011) Nature Reviews Molecular Cell Biology. Aug 23;12(9):551-64. doi: 10.1038/nrm3176. PMCID: PMC3319719

Bruns AF*, Herbert SP*, Odell AF*, Jopling HM, Hooper NM, Zachary IC, Walker JH, Ponnambalam S. Ligand-stimulated VEGFR2 signaling is regulated by co-ordinated trafficking and proteolysis. (2010) Traffic. 11(1), 161-74. doi: 10.1111/j.1600-0854.2009.01001.x. (* equal contribution)

Herbert SP, Huisken J, Kim TN, Feldman ME, Houseman BT, Wang RA, Shokat KM, Stainier DY. Arterial-venous segregation by selective cell sprouting: an alternative mode of blood vessel formation. (2009) Science. Oct 9;326(5950):294-8. doi: 10.1126/science.1178577. PMCID: PMC2865998

Herbert SP, Odell AF, Ponnambalam S, Walker JH. Activation of cytosolic phospholipase A2-a as a novel mechanism regulating endothelial cell cycle progression and angiogenesis. (2009) J Biol Chem. Feb 27;284(9):5784-96. doi: 10.1074/jbc.M807282200. PMCID: PMC2645829.

Hastings AD, Herbert SP, Gawler D, Walker JH. Association with actin mediates the EGTA-resistant binding of cytosolic phospholipase A2-alpha to the plasma membrane of activated platelets. (2009) Cell Biol Int. Jan;33(1):83-91. doi: 10.1016/j.cellbi.2008.09.010.

Herbert SP, Odell AF, Ponnambalam S, Walker JH. The confluence-dependent interaction of cytosolic phospholipase A2-alpha with annexin A1 regulates endothelial cell prostaglandin E2 generation. (2007) J Biol Chem. Nov 23;282(47):34468-78. doi: 10.1074/jbc.M701541200.

Herbert SP, Walker JH. Group VIA calcium-independent phospholipase A2 mediates endothelial cell S phase progression. (2006) J Biol Chem. Nov 24;281(47):35709-16. doi: 10.1074/jbc.M600699200.

Herbert SP, Ponnambalam S, Walker JH. Cytosolic phospholipase A2-alpha mediates endothelial cell proliferation and is inactivated by association with the Golgi apparatus. (2005) Mol Biol Cell. Aug;16(8):3800-9. doi: 10.1091/mbc.e05-02-0164. PMCID: PMC1182317

Grewal S, Herbert SP, Ponnambalam S, Walker JH. Cytosolic phospholipase A2-alpha and cyclooxygenase-2 localize to intracellular membranes of EA.hy.926 endothelial cells that are distinct from the endoplasmic reticulum and the Golgi apparatus. (2005) FEBS J. Mar;272(5):1278-90. doi: 10.1111/j.1742-4658.2005.04565.x.

Howell GJ, Herbert SP, Smith JM, Mittar S, Ewan LC, Mohammed M, Hunter AR, Simpson N, Turner AJ, Zachary I, Walker JH, Ponnambalam S. Endothelial cell confluence regulates Weibel-Palade body formation. (2004) Mol Membr Biol. Nov-Dec;21(6):413-21. doi: 10.1080/09687860400011571.